At present, there is no specific anti monkeypox drugs in China, mainly symptomatic support and treatment of complications.
目前國內(nèi)尚無特異性抗猴痘病毒藥物,主要是對癥支持和并發(fā)癥的治療。
(一)
Symptomatic support treatment. Stay in bed, pay attention to supplement nutrition and water, and maintain the balance of water and electrolyte. For those with high body temperature, physical cooling is the main factor, exceeding 38.5 ℃, and antipyretic analgesics are given to reduce fever, but attention should be paid to prevent collapse caused by massive sweating.
對癥支持治療。臥床休息,注意補(bǔ)充營養(yǎng)及水分,維持水、電解質(zhì)平衡。體溫高者,物理降溫為主,超過38.5℃,予解熱鎮(zhèn)痛藥退熱,但要注意防止大量出汗引發(fā)虛脫。
Keep the skin, mouth, eyes and nose clean and moist, and avoid scratching the skin of the rash to avoid secondary infection. Analgesic drugs can be given when the pain in the rash is serious.
保持皮膚、口腔、眼及鼻等部位清潔及濕潤,避免搔抓皮疹部位皮膚,以免繼發(fā)感染。皮疹部位疼痛嚴(yán)重時可予鎮(zhèn)痛藥物。
(二)Treatment of complications. In case of secondary skin bacterial infection, effective antibiotics should be given, which should be adjusted according to the results of pathogen culture, isolation and identification and drug sensitivity. Prophylactic use of antibiotics is not recommended. When corneal lesions occur, eye drops can be used, supplemented by vitamin A and other treatments. When encephalitis occurs, sedation, dehydration, intracranial pressure reduction, airway protection and other treatments are given.
并發(fā)癥治療。繼發(fā)皮膚細(xì)菌感染時給予有效抗菌藥物治療,根據(jù)病原菌培養(yǎng)分離鑒定和藥敏結(jié)果加以調(diào)整。不建議預(yù)防性應(yīng)用抗菌藥物。出現(xiàn)角膜病變時,可應(yīng)用滴眼液,輔以維生素A等治療。出現(xiàn)腦炎時給予鎮(zhèn)靜、脫水降顱壓、保護(hù)氣道等治療。
(三)Psychological support treatment. Patients often have psychological problems such as tension, anxiety and depression. They should strengthen psychological support, counseling and related interpretation. According to the condition, they should timely ask a psychological specialist for consultation and participate in the diagnosis and treatment of the disease, and give corresponding drug adjuvant treatment when necessary.
心理支持治療。患者常存在緊張、焦慮、抑郁等心理問題,應(yīng)加強(qiáng)心理支持、疏導(dǎo)和相關(guān)解釋工作,根據(jù)病情及時請心理專科醫(yī)師會診并參與疾病診治,必要時給予相應(yīng)藥物輔助治療。
(四)Traditional Chinese medicine treatment. According to the principle of "judging the cause and treating the disease" and "adjusting the three factors", the treatment is based on syndrome differentiation. Those with fever in clinical symptoms are recommended to use Cimicifuga Gegen decoction, Shengsheng powder, Zixue powder, etc; It is recommended to use Qingying Decoction, Cimicifuga Biejia decoction, Xuanbai Chengqi Decoction, etc. for those with clinical symptoms such as high fever, dense pox and rash, sore throat, and multiple lymph node swelling and pain.中醫(yī)治療。根據(jù)中醫(yī)“審因論治”、“三因制宜”原則辨證施治。臨床癥見發(fā)熱者推薦使用升麻葛根湯、升降散、紫雪散等;臨床癥見高熱、痘疹密布、咽痛、多發(fā)淋巴結(jié)腫痛者推薦使用清營湯、升麻鱉甲湯、宣白承氣湯等。
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